🧪 Chemical Properties
O-DSMT HCl (O-Desmethyltramadol Hydrochloride) is a synthetic opioid and the primary active metabolite of Tramadol. The compound is mainly used in chemical, pharmacological, and analytical research to examine interactions at the mu-opioid receptor as well as the inhibition of the norepinephrine transporter. Its chemical formula is C15H23NO2, with a CAS number of 80456-81-1. The molecular weight is 249.35 g/mol (free base) or 285.82 g/mol (hydrochloride form).
The product is provided as the hydrochloride salt, significantly enhancing its water solubility compared to the free base. O-DSMT HCl is supplied as a racemic mixture (approx. 1:1 ratio of the (1R,2R)- and (1S,2S)-enantiomers). The offered variant is characterized by its exceptionally high chemical purity and is free from added impurities or adulterants. This verified grade and form are exclusively available from us.
🏭 Production and Quality Control
Manufacturing is carried out exclusively through a partner laboratory specializing in the synthesis of research compounds according to the highest international quality standards. Each batch undergoes internal verification for chemical identity, purity, and specification compliance. Analytical procedures include HPLC, GC, and mass spectrometry. This ensures that our clients receive a thoroughly verified and reliable compound of unmatched quality and consistency.
🔬 Research Applications
O-DSMT HCl is a fully legal research chemical and is strictly intended for scientific use only. Common applications include:
- Structural analysis (NMR, HPLC, GC, mass spectrometry)
- Receptor binding studies at the mu-opioid receptor
- Transporter interaction studies focused on norepinephrine uptake inhibition
- Comparative pharmacological studies of Tramadol and its metabolites (non-serotonergic focus)
- Method development and validation in chemical or biological matrices
Distribution is limited to qualified professionals with demonstrable research credentials. No sales to private individuals.
🏛️ Institutional Access and Legitimacy Verification
The distribution of this compound is strictly regulated and limited to technical, industrial, and scientific institutions that have successfully completed a legitimacy and identity verification process. This verification ensures that acquisition and use are recognized under current scientific and technical standards. Companies and institutions must provide evidence of valid research or analytical activity prior to purchase authorization.
Distribution to private individuals or non-qualified end users is strictly prohibited. Any use outside of legitimate scientific, industrial, or educational contexts is forbidden and will result in permanent exclusion from further supply.
⚖️ Legal Status and Regulatory Development
At present, O-DSMT HCl is not listed under the German Narcotics Act (BtMG), Medicinal Products Act (AMG), or the New Psychoactive Substances Act (NpSG). Therefore, it remains a fully legal research substance when used for institutional scientific, analytical, or industrial purposes.
However, the German government has announced a forthcoming amendment to the NpSG, which may expand the scope of regulated substance groups. According to the current draft regulation, recognized uses of new psychoactive substances for scientific, industrial, or technical purposes will remain explicitly exempt from prohibition (§ 2(3) NpSG-E). Our distribution policy strictly adheres to this framework, supplying only verified institutions operating under legitimate research or technical mandates.
Clients are advised to remain informed about the current legal situation in their jurisdiction and ensure that acquisition, storage, and use are compliant with applicable laws. Upon the entry into force of future legislative changes, all internal compliance processes and eligibility checks will be automatically updated to maintain full conformity with the revised legal framework.
🚫 Safety and Usage Disclaimer
The use of O-DSMT HCl is subject to strict safety and compliance regulations and is limited to qualified personnel in authorized environments. The following conditions apply:
- Not suitable for ingestion, inhalation, injection, or any form of human or animal consumption.
- Use is restricted to research, analytical, or educational purposes within authorized facilities.
- Must be securely stored and kept inaccessible to unauthorized individuals.
- No redistribution or resale without explicit authorization.
Any violation of these provisions may lead to civil and criminal liability. Users are required to comply with all applicable safety, handling, and disposal regulations for chemical substances.