🧪 Chemical Properties
O-DSMT HCL (O-Desmethyltramadol Hydrochloride) is a synthetic opioid and the primary active metabolite of tramadol. This substance is mainly used in chemical, pharmacological, and analytical research to study interactions at the mu-opioid receptor and to examine the inhibition of the norepinephrine transporter. Its chemical formula is C15H23NO2, and its CAS number is 80456-81-1. The molar mass is 249.35 g/mol (free base) or 285.82 g/mol (hydrochloride form).
The product is offered as the hydrochloride salt, which significantly increases its water solubility compared to the free base. O-DSMT HCL is supplied as a racemic mixture (approximately 1:1 ratio of the (1R,2R)- and (1S,2S)-enantiomers). Our variant is characterized by particularly high chemical purity and is free from added impurities or cutting agents. In this tested quality and form, the product is exclusively available from us.
🏭 Production and Quality Control
The production is carried out exclusively through a partner laboratory specialized in synthesizing research chemicals according to the highest international standards. Each batch undergoes internal testing in our laboratory to verify chemical identity, purity, and compliance with specifications. Analyses include HPLC, GC, and mass spectrometry. This ensures that our customers receive only a tested, pure, and reliable product, which in this combination of production process, internal control, and purity is only available from us.
🔬 Use in Research
O-DSMT HCL is a completely legal research chemical and is intended exclusively for scientific use. Typical applications include:
- Structural chemical analyses (NMR, HPLC, GC, mass spectrometry)
- Receptor binding studies at the mu-opioid receptor
- Transporter interaction studies on norepinephrine reuptake inhibition
- Comparative studies of tramadol and its metabolites (focus on non-serotonergic effects)
- Method development and validation in biological and chemical matrices
The product is supplied only to qualified professionals with proven legitimate research purposes. Any other use is strictly prohibited.
⚖️ Legal Status
O-DSMT HCL is currently not listed under the German Narcotics Act (BtMG), not listed under the Medicines Act (AMG), and not listed under the New Psychoactive Substances Act (NpSG). It is therefore classified as a completely legal research chemical in Germany, and acquisition and possession are permitted under current legal conditions. Customers are required to check the legal status in their own country or region before ordering and ensure compliance with applicable laws. Any misuse is strictly prohibited.
🚫 Safety and Usage Notes
The use of O-DSMT HCL is subject to strict conditions and is exclusively reserved for qualified scientific personnel. The following mandatory notes apply:
- Not suitable for ingestion, inhalation, injection, or any form of consumption.
- Consumption by humans or animals is strictly prohibited.
- For research, analytical, or educational purposes only in authorized facilities.
- Must be stored securely and kept out of reach of unauthorized persons.
- No redistribution to third parties without appropriate authorization.
Violations of these terms may result in civil and criminal consequences. Please observe the applicable safety, storage, and disposal regulations for chemical substances.