Update on the legal situation and future product strategy

Dear community,

The regulatory landscape in Germany is currently undergoing a significant transformation. A core element is the planned expansion of the New Psychoactive Substances Act (NpSG), which will substantially adjust the framework for research, scientific analysis, and the handling of innovative chemical substances. Policymakers have made the objective clear: prevent misuse while enabling legitimate scientific work [2].

The German government has explicitly confirmed that the constitutional principle of legal certainty remains in full effect. This means: no vague catch-all bans, no undefined analog chains, and no retroactive restrictions. Legitimate research remains permitted and predictable.

“Broader formulations [...] would contradict the constitutional requirement of legal certainty and open up endlessly many variants.” [1] [3]

The political directive is clear: yes to public health protection, no to restricting responsible research.

Timeline: Key milestones

  • August 15, 2025: Submission of the draft law to the Federal Council [2]
  • September 26, 2025: Federal Council deliberation; request for broader structure-based bans [3]
  • October 2, 2025: hib communiqué; rejection of blanket analog prohibitions [1]
  • October 8–9, 2025: Presentation of the sixth amendment ordinance [4]
  • Q4 2025: Second reading in Parliament
  • End of 2025: Publication in the Federal Law Gazette
  • Q1 2026: Entry into force with approx. three-month transition period [2]

Transparency and background: decision on October 24, 2025

On October 24, 2025, following publication of updated NpSG documents, we temporarily paused all affected products and removed them from the shop. The trigger was an immediate compliance signal from our monitoring systems.

We identified the regulatory signals on October 10, 2025, conducted full analysis from October 15, 2025, and acted after internal alignment.

Original notice: Important Information on the NpSG (October 24, 2025)

The decision was correct, although communication could have been more proactive. We take that feedback seriously.

We have since strengthened our communication processes:

  • structured communication phases for regulatory events
  • no unannounced assortment changes
  • continuous status updates
  • clear support flows for research customers

Thank you for your trust and constructive feedback.

Transition phase and controlled distribution

Regular sales of affected substances remain paused. Distribution only occurs:

  • with documentation
  • after legitimacy verification
  • and strictly within the legal transition framework

Currently available stock:

Production and quality: our partner laboratory

All mentioned substances are produced exclusively through a specialized partner laboratory. We define specifications, purity standards, and testing procedures, and run regular quality assurance workflows. This ensures reproducible results, documented purity, and reliable supply chains for legitimate research.

Economic impact

The regulatory change affects not only operations but also economics. The substances O-DSMT HCl, SR-17018 HCl and IC-26 HCl generated around 1,500 monthly orders on average. This activity funds a full-time team of three employees, including:

  • full health insurance and social security contributions
  • payroll taxes
  • corporate taxes

The regulatory restriction eliminates a significant revenue segment that previously secured employment, tax revenue, and ongoing research supply. We state this transparently because it reflects the reality of a compliant, responsible business model.

Despite the challenge, we continue to plan and execute responsibly and strategically.

Discounts and returning customer codes

All remaining inventory has been reduced by 15% to support ongoing research work during the transition. This reduction applies to all customers.

Additionally, our 5% returning customer discount continues. This is normally provided via physical voucher cards. Since the last shipping cycle before the sudden temporary pause did not include voucher cards, eligible returning customers will receive a fair alternative:

If you placed an order but did not receive a voucher card, you can simply "generate" your personal discount code. The code equals the final segment of your order ID.

Example:
Order ID: c4e1f2b9-8d54-4af3-91f8-d261e0c8a122
Discount code: d261e0c8a122

This ensures that no existing customer is disadvantaged and everyone who would have received a voucher card still receives the same benefit. If you do not have your order ID at hand, our support team will gladly assist.

O-DSMT HCl

O-DSMT HCl is temporarily sold out.A one-time, controlled restock is planned during the transition period.

Outlook: Stability and scientific alignment

We will continue developing our portfolio responsibly, focusing on:

  • legally secure substance categories
  • scientific relevance
  • verified purity and analytical compliance
  • qualified supply chains

We are also evaluating additional legal substance classes and nature-based and analytical products. New items will only launch after full legal and quality validation.

We continue investing in:

  • supply chain resilience
  • expanded lab reports and CoAs
  • harm-reduction and scientific education
  • digital compliance workflows
  • community feedback and research-driven iteration

Our objective remains a stable, compliant, and research-oriented environment.

Your Remicals.de team

Sources and documents

  1. hib 462/2025; parliamentary briefing Original
  2. Drucksache 21/1504; draft law PDF
  3. Drucksache 21/1927; Federal Council response PDF
  4. Bundesrat 534/25; substance group extension PDF

This article is directly related to one or more of our products – for example, with regard to batches, availability, or quality updates.

We only provide such information via our news.

On the linked product page, you will find additional details about the product and can order or pre-order it directly there.

Available Soon Create Notification

With its dual action as a mu-opioid receptor agonist and norepinephrine reuptake inhibitor, O-DSMT HCL is a versatile research opioid.

The compound is primarily used in studies on tramadol metabolism, receptor affinity, and the absence of serotonergic activity, making it of interest for developing opioid-based substances with improved side effect profiles.

Our version of O-DSMT HCL is produced to the highest standards in a specialized partner laboratory and is laboratory-tested for high purity.

Available Immediately

IC-26 HCL, a structural analogue of methadone, acts as a mu-opioid receptor agonist and is used in research to explore structural modifications within the opioid class.

The substitution of the carbonyl group with a sulfonyl group makes IC-26 HCL particularly valuable for comparative analyses and studies on receptor binding and pharmacodynamics.

Our IC-26 HCL is synthesized exclusively through our partner laboratory, produced to a high-purity standard, and rigorously tested internally for identity and purity.

Available Immediately

SR-17018 HCL is a functionally selective mu-opioid receptor agonist that has attracted significant interest in preclinical research due to its innovative mechanism of action.

The compound is being studied for its potential to provide analgesia with a reduced incidence of typical opioid-related side effects and is suitable for studies on receptor binding dynamics, signal transduction, and biased agonism.

Our SR-17018 HCL is produced exclusively through our partner laboratory and stands out for its exceptionally high chemical purity and batch consistency.

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